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| | | New Acclaim Mixed-Mode WCX-1 Column |  | The Acclaim® Mixed-Mode WCX-1 is a novel, high-efficiency, silica-based column specially designed for separating various basic analytes. This new packing material features a combination of both reversed-phase and weak cation-exchange properties by incorporating a hydrophobic alkyl chain with carboxyl terminus. The Acclaim Mixed-Mode WCX-1 columns feature: - Adjustable selectivity
- Orthogonal selectivity
- Ideal for separating basic analytes – excellent peak shape, sufficient retention, high efficiency
- Multi-retention mechanisms – reversed-phase, cation-exchange, ion-exclusion, and HILIC
- Broad range of applications
The Acclaim Mixed-Mode WCX-1 unique surface characteristics facilitate adjustable selectivity. Retention times can be adjusted by changing mobile phase ionic strength, pH, and organic solvent content, individually or concurrently. The HPLC analysis of basic compounds is often challenging when using reversed-phase silica columns, especially hydrophilic basic compounds. The new Acclaim Mixed-Mode WCX-1 column circumvents these difficulties. It retains basic molecules with symmetrical peak shapes and excellent efficiency. Many application are developed on reversed-phase C18 columns, though secondary analytical methods are often required with orthogonal selectivity. Because of the adjustable selectivity of the Acclaim Mixed-Mode WCX-1 column, it is an ideal column for this purpose.
| | New Acclaim Mixed-Mode WCX-1 Column Specifications | | Column chemistry | Alkyl carboxylic group | | Base silica | Spherical, high-purity | | Particle size | 5µm | | Pore size | 120 Å | | Surface area | 300 m2/g |
| | Order Information | | Acclaim Mixed-Mode WCX, 5 µm (4.6 × 250 mm) | 068352 | | Acclaim Mixed-Mode WCX, 5 µm (4.6 × 150 mm) | 068353 | | Acclaim Mixed-Mode WCX Guard, 5 µm, 2/pk (4.3 × 10 mm) | 068354 | | Guard Kit (Holder and Coupler) | 059526 | | SST Guard Cartridge Holder | 059456 | | Guard to Analytical Column Coupler | 059457 |
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|  |  | Acclaim Mixed-Mode WAX-1 Columns |  | Acclaim® Mixed-Mode WAX columns are packed with a new silica based stationary phase that incorporates both hydrophobic and weak anion-exchange properties. Now simultaneous separation of acids, bases, and neutral molecules can easily be achieved, as well as controlled specific selectivity changes by adjusting the mobile phase. |
| Acclaim Mixed-Mode HILIC-1 Columns | | Acclaim® Mixed-Mode HILIC -1 columns are packed with a new silica-based stationary phase that incorporates both reversed-phase (RP) and hydrophilic interaction liquid chromatography (HILIC) properties |
| Acclaim 120 Reversed-Phase Columns | | The Acclaim® 120 columns are a highly characterized line of LC/MS compatible C18 and C8 phases that have very high surface coverage and very low metal content. These columns provide exceptional performance for a variety of applications in the pharmaceutical, nutraceutical, food, and life science separations areas. |
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