The ProPac® PA1 column is a strong anion-exchange column for the analysis and purification of hydrophilic anionic proteins and peptides with pI values from 3 to 11.
Good for hydrophilic anionic proteins and peptides
Ideal for high-resolution separations of proteins with pI values from 3 to 11
Higher capacity than the DNAPac® PA100
High efficiency and fast mass transport due to the pellicular packing
The ProPac PA1 column is a strong anion-exchange column with quaternary ammonium functional groups attached to a nonporous core particle by means of agglomerated MicroBeadTM resin. This column is well suited to the purification and analysis of hydrophilic anionic proteins and peptides with pI values from 3 to 11. The pellicular nature of the packing provides superior resolution compared to macroporous anion-exchange resins and higher capacity than nonporous anion-exchange resins. The polymeric column body eliminates concern over the effect of metal contamination on the separation.
The ProPac PA1 column is intended for use in the analysis and purification of hydrophilic anionic proteins and peptides. Proteins and peptides that are very hydrophobic (such as integral membrane proteins), or very cationic proteins (e.g., those with very high isoelectric points) may be resolved on this column, but some may exhibit substantial binding to the column. The ProPac PA1 is similar in design to the DNAPac PA100, but with higher capacity and somewhat different selectivity.
