IonPac AS21 Anion-Exchange Column

The IonPac AS21 hydroxide selective anion-exchange column is specifically designed for trace perchlorate in drinking water prior to MS/MS detection. The capacity and selectivity allows for the fast analysis of perchlorate in drinking water at the low µg/L concentration. The AS21 column is the specified column in U.S. EPA Method 331.0.

Recommended anion-exchange column for fast separation of perchlorate prior to MS/MS detection.
Optimized for methylamine or hydroxide mobile phases.
Specified column for U.S. EPA Method 331.0.
Optimum capacity: 45 µeq per column. (2 × 250-mm column).
Operate at ambient or elevated temperatures. Column selectivity is optimized for a 30 °C operating temperature to ensure reproducible retention times in all environmental conditions.
Compatible with HPLC organic solvents that optimize the performance of the electrospray interface (ESI) to a MS or MS/MS detector, modify column selectivity, or for effective column clean up.

The IonPac AS21 hydroxide-selective anion-exchange column is designed for the fast separation of perchlorate in drinking water, ground water, and other matrices prior to detection with MS/MS. The AS21 2 × 250 mm column format was specifically developed with MS/MS compatibility to allow use of volatile mobile phases such as methylamine. The IonPac AS21 is the specified column in U.S. EPA Method 331.0.

IonPac AS21 Anion-Exchange Column Specifications

Dimensions:

IonPac AS21 Analytical Column:
2 × 250 mm

IonPac AG21 Guard Column:
2 × 50 mm

Maximum Operating Pressure:

3000 psi

Mobile Phase Compatibility:

pH 0–14; 0–100% HPLC solvents

Substrate Characteristics:

Bead Diameter and Pore Size:
7 µm (2 × 250 mm); super macroporous resin (2000 Å)
11 µm (2 × 50 mm); microporous resin (<1 Å)

Crosslinking (%DVB): 55%

Ion Exchange Group:

Functional Group: Alkanol quaternary ammonium ion

Functional Group Characteristics:

Ultralow Hydrophobicity

Capacity:

45 µeq (2 × 250-mm analytical column)

1.5 µeq* (2 × 50-mm guard column)

*Guards are packed with a low-capacity microporous resin.

Column Construction:

PEEK with 10–32 threaded ferrule style end fittings. All components are nonmetallic.

Order Information
IonPac AS21 Analytical Column (2 x 250 mm)	063009
IonPac AG21 Guard Column (2 x 50 mm)	063071

Data Sheets
	IonPac AS21 Anion-Exchange Column Data Sheet 1MB
	IonPac AS21 Analytical Column Manual 602K