Performance Examples for the UltiMate 3000 Intelligent LC Series

The UltiMate^® 3000 Intelligent LC series delivers improvements in HPLC performance while ensuring easy and reliable operation. These systems are geared to your chromatography application, setting a new standard for fast and reliable LC. The UltiMate 3000 series operates over wide dynamic flow ranges from preparative to analytic to micro to nano/capillary scales, supporting applications such as discovery processes, quality control, and advanced research like proteomics.

Rapid Separation LC offers extensive flow-pressure capabilities to meet your chromatographic goals. Operating separations in seconds rather than in minutes requires a system that provides excellent precision, speed, and performance. This is provided by the Dionex UltiMate 3000 RSLC system.

• Precise chromatography with both conventional and UHPLC columns [more ]
• Ultra-high precision even at 12 seconds total run time [more]
• More than 50x faster separations compared to conventional HPLC [more]
• Diode Array Detector with up to 100 Hz data collection with full 3-D scan for reliable detection of even the narrowest peaks [more ]
• LC-MS analysis with almost zero carry-over [more]
• The UltiMate 3000 Series features shortest total cycle times [more]
• Stable column temperature even at 100 °C under fluctuating ambient temperature [more ]
• Efficient mobile phase pre-heating even at 100 °C [more]
• Excellent retention time precision even with sub-0.5 min separations [more]
• 36x faster chemical process control application example [more]
• 12x faster analysis of eight softdrink ingredients [more]
• Ultrafast separation of 21 amino acids in 5.5 mins [more ]
• Ultrafast separation of 27 amino compounds in 5.5 min [more]
• High-resolution separation of 27 amino compounds on a 150 mm sub-2 µm columns [more]

The UltiMate 3000 standard system product line provides major advances in performance, reliability, and ease of use.

Performance

• Isocratic retention time precision better than 0.1% RSD [more]
• Gradient retention time precision better than 0.1% RSD [more]
• Total cycle times of 50 s for gradient runs [more]
• Peak area precision typically better than 0.1% RSD [more]
• 0.01% level impurities quantification [more]
• Low detector noise and drift for trace level analysis [more]
• Linear detection up to 2.5 AU [more]
• High injection volume linearity [more]
• Low carryover—typically below the detection limit [more]
• Autosampler temperature accuracy typically better than 1% [more]
• Injection volume accuracy better than 0.2% [more]

Reliability

• Improved system-to-system reproducibility for enhanced method portability [more]
• Reliable temperature control with varying ambient conditions [more]

Ease of use

• Quickly and easily calculate your method validation and related substances results [more]